HomeArchiveVolume 1Volume 1, issue 2Platelet Rich Plasma- mechanism of action and clinical applications
Cristina N. Cozma1, Laura Raducu1,2, Cristian R. Jecan1,2
1Prof. Dr. Agrippa Ionescu Clinical Emergency Hospital, Department of Plastic and Reconstructive Surgery, Bucharest, Romania
2Carol Davila University, Department of Plastic and Reconstructive Surgery, Bucharest, Romania
Abstract

Platelet-rich plasma (PRP) is a blood-derived fraction containing high level of platelets, a high concentration of leukocytes and growth factors. PRP therapy has been growing as a viable treatment alternative for a number of clinical applications and has a potential benefit for use in wound healing.

Nowadays platelet rich plasma is used in stimulating wound healing in skin and soft tissue ulcerations, accelerating wound healing in diabetic patients and facilitating bone proliferation in orthopedic and trauma surgery. It has also applications in maxillofacial surgery, spinal surgery, plastic and esthetic surgery, heart surgery and burns.

This review of the literature shows a limited number of studies realized on humans that sustain PRP applications in orthopedic and plastic surgery. As the use of PRP increases, more properly structured clinical studies are necessary to confirm the results and to establish clearly the techniques of preparing, the conditions and the clinical indications of applying this therapy.

Cite this article:
Vancouver
Cozma CN, Raducu L, Jecan CR. Platelet Rich Plasma- mechanism of action and clinical applications. J Clin Investig Surg. 2016 Nov 25;1(2):41-46. Available from: https://www.proscholar.org/jcis/archive/vol.1/iss.2/1/ doi: 10.25083/2559.5555.12.4146
NLM
Cozma CN, Raducu L, Jecan CR. Platelet Rich Plasma- mechanism of action and clinical applications. J Clin Investig Surg. 2016 Nov;1(2):41-46. doi: 10.25083/2559.5555.12.4146.
AMA
Cozma CN, Raducu L, Jecan CR. Platelet Rich Plasma- mechanism of action and clinical applications. J Clin Investig Surg. 2016;1(2):41-46.
MLA
Cozma, Cristina N., et al. “Platelet Rich Plasma- mechanism of action and clinical applications.” Journal of Clinical and Investigative Surgery 1.2 (2016): 41-46. doi:10.25083/2559.5555.12.4146.
APA
Cozma, C. N., Raducu, L., & Jecan, C. R. (2016). Platelet Rich Plasma- mechanism of action and clinical applications. Journal of Clinical and Investigative Surgery, 1(2), 41-46.
ISO 690
Cozma
, Cristina N., et al. Platelet Rich Plasma- mechanism of action and clinical applications. Journal of Clinical and Investigative Surgery, 2016, 1.2: 41-46.