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Toma I. Papacocea1, Danil Adam1, Mirela Renta2, Ioana R. Papacocea3

1Carol Davila University, Department of Neurosurgery, St. Pantelimon Hospital, Bucharest, Romania
2Bagdasar-Arseni Emergency Hospital, Department of Neurosurgery, Bucharest, Romania
3Carol Davila University, Department of Physiology, Bucharest, Romania


The concomitant presence of the olfactory groove meningioma with uterine fibrosis is very rare. Our report presents the case of a giant olfactory groove meningioma revealed after a uterine fibroma resection in a 44 years-old female, due to a generalized seizure 10 days after operation.

Cranial CT-scan identified the tumor as an olfactory groove meningioma. The tumor was operated with a macroscopically complete resection; the endothermal coagulation of the dura attachment was performed (Simpson II) with a good postoperative evolution. Laboratory results showed the presence of receptors for steroid hormones both in meningioma and uterine tumor, and the histopathological examination revealed an atypical meningioma with 17% proliferation markers.

Our findings suggest that even though meningiomas are benign tumors and a complete resection usually indicates a good prognosis, the association with uterine fibromatosis and the presence of high percentage of steroid receptors creates a higher risk to relapse, imposing therefore a good monitoring.