Journal of Clinical and Investigative Surgery
ISSN: 2559-5555


Atypical olfactory groove meningioma associated with uterine fibromatosis; case report

Toma I. Papacocea1, Danil Adam1, Mirela Renta2, Ioana R. Papacocea3

1Carol Davila University, Department of Neurosurgery, St. Pantelimon Hospital, Bucharest, Romania
2Bagdasar-Arseni Emergency Hospital, Department of Neurosurgery, Bucharest, Romania
3Carol Davila University, Department of Physiology, Bucharest, Romania

J Clin Invest Surg. 2016; 1(2): 84-88. DOI: 10.25083/2559.5555.12.8488
Running title: Olfactory groove meningioma and uterine fibromatosis
Keywords: olfactory groove meningioma, uterine fibromatosis, association


The concomitant presence of the olfactory groove meningioma with uterine fibrosis is very rare. Our report presents the case of a giant olfactory groove meningioma revealed after a uterine fibroma resection in a 44 years-old female, due to a generalized seizure 10 days after operation.

Cranial CT-scan identified the tumor as an olfactory groove meningioma. The tumor was operated with a macroscopically complete resection; the endothermal coagulation of the dura attachment was performed (Simpson II) with a good postoperative evolution. Laboratory results showed the presence of receptors for steroid hormones both in meningioma and uterine tumor, and the histopathological examination revealed an atypical meningioma with 17% proliferation markers.

Our findings suggest that even though meningiomas are benign tumors and a complete resection usually indicates a good prognosis, the association with uterine fibromatosis and the presence of high percentage of steroid receptors creates a higher risk to relapse, imposing therefore a good monitoring.