Journal of Clinical and Investigative Surgery
ISSN: 2559-5555


Cholecystectomy in cirrhotic patients – how safe is it?

Petrișor Banu1,2, Vlad D. Constantin1,2, Florian Popa1,2, Ion Motofei1,2, Cristian Bălălău1,2

1Carol Davila University, Department of Surgery, Bucharest, Romania
2St. Pantelimon Hospital, Department of Surgery, Bucharest, Romania

J Clin Invest Surg. 2017; 2(1): 1-7. DOI: 10.25083/2559.5555.21.17
Running title: Cholecystectomy in cirrhotic patients; how safe is it
Keywords: cholecystectomy, gallstones, cirrhosis, safety


Liver cirrhosis is a major health problem worldwide with a prevalence that varies greatly from one geographical area to another.

Besides the risk factors common to the general population to develop gallstone disease such as advanced age, female sex or positive family history of gallstones, in patients with liver cirrhosis there are additional risk factors that contribute to the occurrence of gallstones. They are more frequent in patients with a longer duration of the disease and in Child B and C stages. Gallstones disease occurs three times more frequently in patients with liver cirrhosis than in non-cirrhotic patients.

Surgery is required if symptoms or complications related to the presence of gallstones occur and a thorough preoperative evaluation and optimization of patient’s condition is necessary prior to surgery.

The procedure of choice in these situations is laparoscopic cholecystectomy. The technique has some particularities resulting from local anatomical changes and conversion to open technique remains low and morbidity and mortality rates are within acceptable limits.