Journal of Clinical and Investigative Surgery
ISSN: 2559-5555


Does sentinel lymph node detection play a role in patients with vaginal cancer?

Nicolae Bacalbasa1,2,3, Irina Balescu4, Mihai Dimitriu5, Cristian Balalau5 Mihaela Vilcu1,2, Iulian Brezean1,2

1Ion Cantacuzino Clinical Hospital, Bucharest, Romania
2 Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
3Center of Excellence in Translational Institute, Fundeni Clinical Institute, Bucharest, Romania
4Ponderas Academic Hospital, Bucharest, Romania
5St. Pantelimon Emergency Clinical Hospital, Bucharest, Romania

J Clin Invest Surg. 2019; 4(1): 1-4. DOI: 10.25083/2559.5555/4.1/1.4
Running title: Sentinel node detection in vaginal cancer
Keywords: sentinel lymph node biopsy, vaginal cancer, lymphadenectomy


The role of sentinel lymph node detection was clearly demonstrated in patients diagnosed with gynecologic malignancies such as breast, endometrial, cervical or vulvar cancer. Therefore, the method provides an adequate staging of the disease with minimal postoperative complications when compared to classical extended lymphadenectomy. Recently, the method has been successfully reported in vaginal cancer patients. This is a literature review of the current papers published so far on the issue of sentinel lymph node detection in vaginal cancer patients.

Although only few cases have been reported so far, it seems that sentinel lymph node biopsy in vaginal cancer patients represents a safe, effective and feasible method to diminish the rates of unnecessary extended lymph node dissection in vaginal cancer patients. However, due to the rarity of the disease in association with the low number of cases reported so far, the method is not part of the therapeutic standard protocol for this disease, larger studies still being needed.