{"id":1056,"date":"2021-07-20T09:46:39","date_gmt":"2021-07-20T09:46:39","guid":{"rendered":"https:\/\/www.proscholar.org\/jcis\/?page_id=1056"},"modified":"2021-07-20T09:46:39","modified_gmt":"2021-07-20T09:46:39","slug":"8","status":"publish","type":"page","link":"https:\/\/www.proscholar.org\/jcis\/publications\/vol.6\/iss.1\/8\/","title":{"rendered":"Volume 6, issue 1, pp. 43-47"},"content":{"rendered":"<p>Objective. We aimed to demonstrate whether the immunohistochemical expression of C-erb-B2 and progesterone receptors are valuable in the diagnosis of intraepithelial cervical neoplasia and squamous cell carcinoma. Methods and Results. Our retrospective study, a total of 84 cases diagnosed as squamous cell carcinoma and cervical intraepithelial neoplasia during 2005-2009, at the pathology department of Harran University, was investigated and stained with immunohistochemistry. Progesterone receptor was stained positive in 5 of 21 cervical intraepithelial neoplasia I. As a result of the statistical analysis (SPSS statistic 15.0), a significant correlation was found for positive progesterone receptors. No positive staining was seen in any of the cases with CerbB2 (p&gt;0,05). Conclusions. In this study, it was concluded that positive progesterone receptors can be used to distinguish cases of cervical intraepithelial neoplasia I from other dysplasia and carcinoma, while Cerb-B2 has not been shown to be useful in distinguishing between these lesions.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Objective. We aimed to demonstrate whether the immunohistochemical expression of C-erb-B2 and progesterone receptors are valuable in the diagnosis of intraepithelial cervical neoplasia and squamous cell carcinoma. Methods and Results. Our retrospective study, a total of 84 cases diagnosed as squamous cell carcinoma and cervical intraepithelial neoplasia during 2005-2009, at the pathology department of Harran [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1023,"menu_order":8,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"publication_category":[9],"class_list":["post-1056","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Volume 6, issue 1, pp. 43-47 - Journal of Clinical and Investigative Surgery<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.proscholar.org\/jcis\/publications\/vol.6\/iss.1\/8\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Volume 6, issue 1, pp. 43-47 - Journal of Clinical and Investigative Surgery\" \/>\n<meta property=\"og:description\" content=\"Objective. We aimed to demonstrate whether the immunohistochemical expression of C-erb-B2 and progesterone receptors are valuable in the diagnosis of intraepithelial cervical neoplasia and squamous cell carcinoma. Methods and Results. Our retrospective study, a total of 84 cases diagnosed as squamous cell carcinoma and cervical intraepithelial neoplasia during 2005-2009, at the pathology department of Harran [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.proscholar.org\/jcis\/publications\/vol.6\/iss.1\/8\/\" \/>\n<meta property=\"og:site_name\" content=\"Journal of Clinical and Investigative Surgery\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.proscholar.org\/jcis\/publications\/vol.6\/iss.1\/8\/\",\"url\":\"https:\/\/www.proscholar.org\/jcis\/publications\/vol.6\/iss.1\/8\/\",\"name\":\"Volume 6, issue 1, pp. 43-47 - Journal of Clinical and Investigative Surgery\",\"isPartOf\":{\"@id\":\"https:\/\/www.proscholar.org\/jcis\/#website\"},\"datePublished\":\"2021-07-20T09:46:39+00:00\",\"dateModified\":\"2021-07-20T09:46:39+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.proscholar.org\/jcis\/publications\/vol.6\/iss.1\/8\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.proscholar.org\/jcis\/publications\/vol.6\/iss.1\/8\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.proscholar.org\/jcis\/publications\/vol.6\/iss.1\/8\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.proscholar.org\/jcis\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Publications\",\"item\":\"https:\/\/www.proscholar.org\/jcis\/publications\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Volume 6\",\"item\":\"https:\/\/www.proscholar.org\/jcis\/publications\/vol.6\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Volume 6, issue 1\",\"item\":\"https:\/\/www.proscholar.org\/jcis\/publications\/vol.6\/iss.1\/\"},{\"@type\":\"ListItem\",\"position\":5,\"name\":\"Volume 6, issue 1, pp. 43-47\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.proscholar.org\/jcis\/#website\",\"url\":\"https:\/\/www.proscholar.org\/jcis\/\",\"name\":\"Journal of Clinical and Investigative Surgery\",\"description\":\"JCIS\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.proscholar.org\/jcis\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Volume 6, issue 1, pp. 43-47 - Journal of Clinical and Investigative Surgery","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.proscholar.org\/jcis\/publications\/vol.6\/iss.1\/8\/","og_locale":"en_US","og_type":"article","og_title":"Volume 6, issue 1, pp. 43-47 - Journal of Clinical and Investigative Surgery","og_description":"Objective. 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