2013

The first stage

The first stage of this study was nearly four months; it took place between September 02, 2013 and December 20, 2013, having the following objectives: establishing team, tasks, and technical setting of the study. As specific activities, this stage implied: assignment of responsibilities, administrative activities, documentation and organization.

Regarding research activities scheduled to take place during this study, it was performed a review of the literature data that were considered of interest to the research topic, a process that continued during the following stages of the study. The establishment process of the team was completed for this stage, setting specific/ clear tasks and duties for each person of the team.

The logistic activities related to the acquisition process of ecquipments for deployment of the study has been fully completed, buying all reactives/ ecquipments that were included in the project for this stage. Storage and use of substances that will be used for hormonal dosages in the next stages were established, and technical conditions for conducting the study were established. A clinical study configuration was also developed (that started in the second stage), so as to allow centralization, interpretation and dissemination of data once the partial results were obtained.

There were established the following objectives for this project:  

  • To verify whether there is/ can be identified on men the existence of two distinct bio-psycho-sexual profiles. In this respect it will be investighed the existence of possible interrelation between the dominant hand, psychological profile, sexual orientation and sexual dependence by androgen activation (through side effects that occur after administration of 5α-reductase inhibitors, such as finasteride).
  • To verify if variation of the plasmatic level of dihydrotestosterone (induced by administration of 5α reductase inhibitors) is correlated with the magnitude of sexual side effects. In this respect, it was established that subjects taking finasteride will be informed about possible sexual side effects that could be inhibitory or, conversely, stimulatory. We will also investigate if variation of the plasmatic level of dihydrotestosterone (pharmacologically induced) correlates with the magnitude of sexual side effects.
  • To verify if there is a possible practical application of the two supposed bio-psycho-sexual profiles.

Scientific results obtained during this project are foreseen to be disseminated through national and international communications (conferences, congresses, etc.) and in the form of articles, as partial results starting from the second stage, and as well as in the form of final results (from the third stage of the project).

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